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Epidemiology: Malaria and Diarrhoea


However, its role as compared to bacterial, viral, and parasitic pathogens causing diarrhoea remains unclear. In a case-control study among 240 paediatric patients with acute diarrhoea and 120 control children in Tamale, viral, bacterial, and parasitic pathogens causing diarrhoea are examined. These examinations take place being part of a capacity building project in Tamale and Berlin. Viral infections, rotavirus in particular, predominate as causes of acute diarrhoea in Tamale, northern Ghana. Malaria plays a comparatively inferior role in this regard.

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Project Details

Principal Investigator:
Prof. Dr. med. Frank P. Mockenhaupt

Antje Tomschegg
Bärbel Jakob
Dr. Thomas Weitzel
Susanne Röwer

Co-workers, Ghana:
Andrea Djie-Maletz
Dr. Eiman Saad
Dr. Felicia Amoo-Sakyi
Dr. Klaus Reither
Francis Danikuu
Louis Anyidoho
Peter Ziniel
Stephen Danour

Dr. Rowland Otchwemah, School of Medicine and Health Sciences, Tamale, Ghana
Dr. Elias Sory, Dr. Andrew Seidu, Ministry of Health, Tamale, Ghana
Prof. Klaus Stark, Dr. Eckart Schreier, Robert-Koch-Institut, Berlin
PD Dr. Ralf Ignatius, Institut für Mikrobiologie und Hygiene, Charité, Berlin
Dr. Teunis Eggelte, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, Amsterdam, Holland

Doctoral students:

Project duration:

Project status:
Pilot study

Charité, Robert-Koch-Institute, German Rotary Volunteer Doctors, Industry


Silva PA, Stark K, Mockenhaupt FP, Reither K, Weitzel T, Ignatius R, Saad E, Seidu-Korkor A, Bienzle U, Schreier E. Molecular characterization of enteric viral agents from children in northern region of Ghana. J Med Virol. 2008 Oct;80(10):1790-8.

Djie-Maletz A, Reither K, Danour S, Anyidoho L, Saad E, Danikuu F, Ziniel P, Weitzel T, Wagner J, Bienzle U, Stark K, Seidu-Korkor A, Mockenhaupt FP, Ignatius R. High rate of resistance to locally used antibiotics among enteric bacteria from children in Northern Ghana. J Antimicrob Chemother. 2008 Jun;61(6):1315-8.

Reither K, Ignatius R, Weitzel T, Seidu-Korkor A, Anyidoho L, Saad E, Djie-Maletz A, Ziniel P, Amoo-Sakyi F, Danikuu F, Danour S, Otchwemah RN, Schreier E, Bienzle U, Stark K, Mockenhaupt FP. Acute childhood diarrhoea in northern Ghana: epidemiological, clinical and microbiological characteristics. BMC Infect Dis. 2007 Sep 6;7:104.

Weitzel T, Reither K, Mockenhaupt FP, Stark K, Ignatius R, Saad E, Seidu-Korkor A, Bienzle U, Schreier E. Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana. J Clin Microbiol. 2007 Aug;45(8):2695-7.